Onderzoek: veiligheid en effecten van NMN-suppletie op NAD+ niveaus

Research: How NMN Supplements Contribute to Increasing NAD+ and Vitality

The study investigated the effects of oral intake of nicotinamide mononucleotide (NMN) in healthy Japanese men, focusing on safety and the impact on NAD+ levels. The participants received different dosages of NMN (100, 250, 500 mg), and the results showed that NMN was well tolerated, with no serious side effects. Moreover, a dose-dependent increase in NAD+ and its metabolites was observed.

No significant effects on sleep quality, eye health, or vital functions were found. The increased concentrations of NAD+ metabolites indicate an efficient metabolism of NMN, even at higher dosages.

The study suggests that NMN may be a promising supplement to slow down aging processes, given the increase in NAD+ levels and the absence of adverse effects. However, more research with larger groups is needed to further confirm the clinical benefits of NMN.

The study highlights several benefits of NMN supplements:

  1. Increase of NAD+ levels: NMN supplementation effectively increased NAD+ and its metabolites, which are essential for energy production and slowing down aging processes.

  2. Good tolerability: NMN was well tolerated by the participants, even at higher dosages, without serious side effects.

  3. Potential support for healthy aging: By increasing NAD+ levels, NMN may help counteract age-related decline, which can be beneficial for the health of cells and body functions in the long term.

These findings suggest that NMN supplements are potentially safe and effective for healthy aging.
Source: [PubMed](https://pubmed.ncbi.nlm.nih.gov/31685720/)

Back to blog

Order one of our Premium NMN products now.

  • Highest purity & maximum biological uptake

    We opt only for the highest quality supplements, ensuring maximum absorption by the body. For instance, our NMN boasts a purity level of >99.8%.

  • Independently laboratory tested

    All supplements undergo double testing and verification in a laboratory for quality, including in NL(EU) or USA.

  • High-quality production (GMP)

    Our supplements are produced according to strict requirements for good and safe production, adhering to various ISO standards within this framework.

  • Nieuwe humane studie naar magnesium L-threonaat (Magtein®): wat zeggen de resultaten écht?

    New human study on magnesium L-threonate (Magte...

    Magnesium supplements are more popular than ever, but not every form of magnesium gets the same level of scientific attention. One of the most discussed forms in recent years is...

    New human study on magnesium L-threonate (Magte...

    Magnesium supplements are more popular than ever, but not every form of magnesium gets the same level of scientific attention. One of the most discussed forms in recent years is...

  • Nieuwe humane studie: NMN verhoogt NAD⁺ bij mensen, en het darmmicrobioom lijkt een sleutelrol te spelen

    New human study: NMN increases NAD⁺ in humans, ...

    In January 2026, an interesting new human study was published in the scientific journal Nature Metabolism. The researchers compared three well-known NAD⁺ precursors: NMN (Nicotinamide Mononucleotide) Nicotinamide Riboside (NR) Nicotinamide...

    New human study: NMN increases NAD⁺ in humans, ...

    In January 2026, an interesting new human study was published in the scientific journal Nature Metabolism. The researchers compared three well-known NAD⁺ precursors: NMN (Nicotinamide Mononucleotide) Nicotinamide Riboside (NR) Nicotinamide...

  • Meer dan een sport­supplement: de rol van creatine in hersenenergie

    More than a sports supplement: the role of crea...

    Although creatine is best known as a supplement for muscle performance, the molecule also plays an important role in the brain’s energy metabolism. The brain uses about 20% of the...

    More than a sports supplement: the role of crea...

    Although creatine is best known as a supplement for muscle performance, the molecule also plays an important role in the brain’s energy metabolism. The brain uses about 20% of the...

1 of 3