Onderzoek: hoe NMN-suppletie gezonde veroudering en NAD+-niveaus verhoogt

The search for a quick and affordable NAD+ measurement

In this study, researchers developed an innovative NAD+ testing method that uses a bioluminescent sensor based on E. coli. This allows NAD+ levels to be quickly measured with just 5 μL of blood from a finger prick. This new method enables easy and inexpensive monitoring of NAD+ levels without the need for expensive laboratory equipment such as HPLC-MS. Additionally, the bioluminescent sensor offers an accurate and scalable solution for analyzing large numbers of samples.

The power of NMN and sports: boost for NAD+

The study demonstrated that both oral NMN supplements and physical activity cause a significant increase in NAD+ levels in the blood. In a clinical study with two dosages of NMN (500 mg and 1000 mg per day), both dosages were found to significantly increase NAD+ levels, depending on the dose. Additionally, exercise combined with NMN resulted in even higher NAD+ values. These findings suggest that NMN supplements and physical activity can be important ways to promote NAD+ levels and thereby health.

Women, men and NAD+: who has the advantage?

The finger-prick NAD+ measurements revealed that there are clear differences in NAD+ levels between men and women, especially before the age of 50. Men were found to have higher average NAD+ levels than women, but after the age of 50, these differences fade. Additionally, there is a clear age-dependent decline in NAD+ levels, which is more pronounced in men than in women. These differences may play a role in understanding aging processes and the development of personalized anti-aging therapies.

Benefits of NMN supplements

  • Increased NAD+ levels in the blood, which is essential for energy production and healthy aging.
  • Improved response to physical activity, which can contribute to better overall health.
  • The possibility for a personalized approach to aging through regular monitoring of NAD+ levels.

Research conclusions

The study shows that NMN supplements are effective in increasing NAD+ levels and that this increase is enhanced by physical activity. The new, affordable testing method offers opportunities for personalized health therapies focused on NAD+ and aging. The findings support the potential of NMN supplementation as an intervention to counteract aging and improve overall vitality.

Source: https://onlinelibrary.wiley.com/doi/10.1111/acel.13965

Back to blog

Order one of our Premium NMN products now.

  • Highest purity & maximum biological uptake

    We opt only for the highest quality supplements, ensuring maximum absorption by the body. For instance, our NMN boasts a purity level of >99.8%.

  • Independently laboratory tested

    All supplements undergo double testing and verification in a laboratory for quality, including in NL(EU) or USA.

  • High-quality production (GMP)

    Our supplements are produced according to strict requirements for good and safe production, adhering to various ISO standards within this framework.

  • Meer dan een sport­supplement: de rol van creatine in hersenenergie

    More than a sports supplement: the role of crea...

    Although creatine is best known as a supplement for muscle performance, the molecule also plays an important role in the brain’s energy metabolism. The brain uses about 20% of the...

    More than a sports supplement: the role of crea...

    Although creatine is best known as a supplement for muscle performance, the molecule also plays an important role in the brain’s energy metabolism. The brain uses about 20% of the...

  • Creatine en spierkracht: het wetenschap­pelijke geheim achter explosieve prestaties

    Creatine and muscle strength: the scientific se...

    Creatine monohydrate is among the most thoroughly researched dietary supplements in the field of sports performance. In muscle cells, creatine plays a central role in the so-called creatine-phosphocreatine system, which...

    Creatine and muscle strength: the scientific se...

    Creatine monohydrate is among the most thoroughly researched dietary supplements in the field of sports performance. In muscle cells, creatine plays a central role in the so-called creatine-phosphocreatine system, which...

  • Magnesium L-threonaat en hersenmagnesium

    Magnesium L-threonate and brain magnesium

    Magnesium is an essential mineral for the functioning of the nervous system. Nevertheless, research shows that increasing magnesium levels in the brain is not straightforward. Many traditional magnesium salts do...

    Magnesium L-threonate and brain magnesium

    Magnesium is an essential mineral for the functioning of the nervous system. Nevertheless, research shows that increasing magnesium levels in the brain is not straightforward. Many traditional magnesium salts do...

1 of 3